P206 Arterial stiffness and functional state of the left and right parts of the heart in adult patients with cystic fibrosis

Pulmonary hypertension and cor pulmonale have been shown to worsen prognosis increase the risk of death in adult patients with cystic fibrosis (CF). To evaluate arterial stiffness (AS) functional state left right parts heart CF patients. 50 (25 M/ 25 F, mean age 26 ± 6 yrs) 52 volunteers (20 32 27 were examined. Echocardiography was performed only AS measurements using VaSera VS-1500N: cardio-ankle vascular index (CAVI) ankle-brachial (ABI) analyzed. CAVI (R-CAVI L-CAVI) control group are comparable reference values: 6.5 0.9 0.8 vs 6.0 1.6 6.3 1.2 (the value CAVI<8.0). Similar results obtained analysis ABI index. Dilatation cavities not detected Stroke volume – 46.9 11.6 ml, ventricular ejection fraction 62.9 4.5%, systolic pressure pulmonary artery (sPAP) 25.3 3.3 mmHg, TAPSE 26.6 1.7 mm. Arterial does differ between healthy volunteers. Its use as a predictor cardiovascular events is informative. In our there no decrease function ventricles, sPAP normal. There significant correlations echocar-diographic parameters.